Online ISSN: 2515-8260

Keywords : Asthma

Comparison between the presence of cow milk protein allergy in asthmatic and non-allergic children

Hadeel I. Enany, M. H. M. Ebrahim, E. M. Rasheed, Eman M. Elbehedy, Shereen A. Baioumy

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 448-456

Background: Hypersensitivity to cow milk proteins is one of the main food allergies
and affects mostly but not exclusively infants, while it may also persist through
adulthood and can be very severe. Different clinical symptoms of milk allergy have
been established. The diagnosis of milk allergy differs widely due to the multiplicity
and degrees of symptoms, and can be achieved by skin or blood tests. The aim of
this study to assess the role of cow milk (CM) to induce asthma and compare
between the presence of cow milk protein allergy in asthmatic and non-allergic
children and to prevent occurrence of asthma among children, Subjects and
methods: This is a case control study, was conducted on 154 patients divided into
two groups (77 in each). This study was conducted in Pulmonology Unit of
Pediatric Department in Zagazig University Hospital. Result: There was high
statistically significant difference between the two studied groups as regards skin
pick test. There was high significant increase in the severity recorded in respiratory
function test in allergic group compared to control group. Conclusion: our study
showed that CMA can exacerbate the symptoms in children with asthma. Therefore,
it is worth considering a possible role of food allergy in asthma in young children,
particularly when asthma is not adequately controlled in spite of proper routine
management. Although SPT seemed to be more reliable than sIgE testing, both had
suboptimal reliability. A definite decision should depend on performing a titrated
oral challenge test.



European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 1075-1082
DOI: 10.31838/ejmcm.07.09.110

The goal of the random group experimental research was to figure out the impact of yoga therapy on the peak expiratory flow rate (PEFR) of asthmatic adult women and stress. For the purposes of the study, 30 adult asthmatic women were randomly selected using the Chennai random group sampling method between the ages of 45 and 55 and were divided into two groups, A and B, each with 15 subjects. It was speculated that substantial discrepancies within the control group on selected physiological and psychological variables among asthmatic adult women would occur due to Yoga Therapy. The pre-test on the chosen physiological variable such as Peak Expiratory Flow Rate (PEFR) and psychological variable such as Stress before the start of the training program was conducted for both groups (A and B).Yoga Therapy was given to Group A; Group B (Control Group) received no specific treatment, but were in active rest after the trial duration of eight weeks, all groups were retested on the selected dependent variables. The dependent variables tested were measured and compared using the Study of Co-variance (ANCOVA) approach to figure out the essential variations between the classes. The importance test has been set at a confidence level of 0.05. There was a major increase in the peak expiratory flow rate (PEFR) and depression after eight weeks of yoga therapy. Group A remained significantly relevant relative to Group B at the conclusion of the intervention; it is concluded that yoga therapy had a significant impact among asthmatic adult women on physiological and psychological variables. Yoga therapy is therefore useful in increasing the Peak Expiratory Flow Rate (PEFR) and overcoming stress for asthmatic adult women.


Dr. Sanjay D. Gabhale; Dr. Preetha Anand; Dr. Rahul VC Tiwari; Dr. Heena Tiwari; Dr.Savitri Ranjeri; Dr. Abhinav Vilas Lambe

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 6606-6612

Aim: Purpose of our research is to establish the increased incidence of asthma with adolescent age group
Methodology: A cross-sectional, school-based study carried out amongst 1200 children. In
our study, we took into consideration about various demographic patterns like lifestyle
patterns, health issues, as well a comparison between asthmatics and non- asthmatics.
Comparison between the two groups was done by analysing data using Statistical Analysis
Software 25.0.
Results: Among a final sample of 1198 participants, the prevalence of self-reported asthma
was found to be 8.2%. Various characteristics were found significantly different between
the 2 groups including the gender, the weight and dietary patterns. Self –reported
asthmatic were more likely to be males, overweight or obese.
Conclusion: Asthma disease remains prevalent among adolescents and requires higher
awareness and better guidance for its prevention and treatment. Further efforts should
focus on health promotion and as well as improved quality of life so as to prevent this
chronic disease.

Influence of mouth breathing on oral health in children: A population-based crosssectional study in Nagpur city

Dr. Arunkumar Sajjanar; Dr. Nilesh Rojekar; Dr. Pankaj Chavan; Dr. Milind Wasnik; Dr. Niharika Gahlod; Dr. Harshita Shukla

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 7652-7659

Previous studies have suggested that mouth breathing has harmful effects on oral health in
children, but the evidence has been insufficient. To investigate the association of mouth
breathing with oral health in school children aged 8–11 years from Nagpur city , India
Materials and methods
Cross-sectional data were obtained from March to April 2019. A questionnaire was used to
investigate children's mouth breathing habits and personal/family histories related to allergic
disease. Oral health status was determined through a clinical oral examination. Data were
analyzed with multivariable logistic regression.
In total, 1007 children were included. We observed no association between mouth breathing
and dental caries in children. However mouth breathing was associated with child's tonsillitis
and was identified as a possible risk factor for class II dental malocclusion.

Role of Herbal Medication in Treatment of Asthma

Satish Kumar Sharma; Isha Talwar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 6, Pages 1016-1025

Asthma is the most prevalent non-transmissible disease that entirely affects quality of life. Management of such diseases is a pre-requisite. . Modern biological therapy for extreme asthma care, along with biomarker advances, provide the potential for phenotypic-specific therapies and introduction of more tailored procedures. Although many measures were adopted to overcome from this issue but still some side effects are faced while using synthetic medications. The present review discusses about herbal medication that were adopted by different countries to cure asthma. Discussion of Chinese, Japanese, Indian and alike herbs were done along with their clinical trials conducted on different subjects. Final a conclusion is drawn wherein it is observed that herbal medications were effective in treating asthma but a full reliance over them may sometime cause serious consequences as it not always herbs are found to be effective on different subjects. The reason may be due to mis-guiding during preparation of the formulation or incorrect labelling of the formulation

Systematic review on Asthma and Irritants

Dr.Dinesh Kumar S; Dr. Amarendiran

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 5357-5364

Asthma is an infectious condition which is heterogeneous and characterized by enhanced airway hyper response to external stimuli including irritants. Asthmatics could be more prone to environmental irritants than healthy citizens, that is, to react in lower quantities. The study also checked the empirical assistance for this speculation and analysed in what manner asthma is taken into consideration when establishing dosage limits and guideline values. The study found that experiments compared stable and asthmatic people are sometimes inconclusive. However, the available reports are underused by business and specialist committees respectively. Data for certain irritants show that asthmatics are three times more responsive than safe. The most plentiful data on sulphur dioxide found. A benchmark concentration study here showed a 9-fold intensity gap. Based on such results, when establishing exposure limits and recommendations for irritants a default measurement factor is recommended.