Online ISSN: 2515-8260

Keywords : pain syndrome


Improvement Of Treatment Protocols Of Pain Syndrome In Patients With Chronic Brucellosis

Zafar Z. Aminov; Sohiba Z. Khakimova; Salim S. Davlatov

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 2540-2545

Despite the fact that brucellosis is a particularly dangerous, socially significant endemic infectious disease, to date, there are very few published scientific research on complex treatment, taking into account the pathogenetics of the disease.
Materials and methods. The data of 52 patients, with a diagnosis of chronic brucellosis accompanied by pain syndrome, were analyzed. Based on the received treatment, all patients were divided into 3 groups. The dynamics of treatment was evaluated by laboratory tests, and the perception of pain was evaluated by a 10-point visual analogue scale.
Results. The analysis showed that in all groups there was a positive trend, but the trend of the dynamics was different. The highest rate of improvement in the general condition of patients and reduction of pain was observed in the third group (p-trend<0.0001), which received B vitamins, along with antibiotic therapy and non-steroidal anti-inflammatory drugs (NSAIDs). A lower rate of improvement was observed in the group of patients receiving antibiotic therapy and NSAIDs.
Conclusions. Treatment of chronic brucellosis should be rational and comprehensive, taking into account neurological symptoms, the course, the nature and severity of the pain syndrome. It is advisable to prescribe vitamins of group B, along with NSAIDs and antibiotics, to provide a more rapid improvement in the general condition of the patient.

Application Of Radiofrequency Neuroablation In Degenerative Osteoarthritis Of The Hip And Knee Joints

Akramov Vohid Rustamovich; Asilova Saodat Ubayevna; Shirinov Dilshod Kudratovich; Ruzibaev Dilmurod Ruzimetovich; Nazarov Ravshan Bakhodirovich

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 6, Pages 3030-3039

Annotation. Ablation (denervation of sensory nerves) is a new simpler and more effective method of treatment. RF denervation of the sensory nerves of the TBS in the treatment of coxalgia, CS - in the treatment of osteoarthritis. The latter are most widely used by the method of RF ablation (RFA) of the obturator and femoral nerves in osteoarthritis of the hip joint and knee joint without surgery. We performed it in 35 patients with coxarthrosis and in 25 with gonoarthrosis. The patients underwent Doppler and X-ray MRI, ultrasound, examination. All patients underwent neuroablation by the method developed by us. assessed the results of treatment according to the U. Oberg scale, good and very good results were considered when the patients had no pain in the joints when walking and at rest, the increase in the range of motion of the joints and normal walking were also taken into account. In patients with osteoarthritis of large joints, patients with 1 month - 85.5%, 3 months - 89.3%, 6 months - 82.5%, 12 months - 78.5%. .. The duration of remission has increased for at least 9 months. Unsatisfactory results were observed in 3% of patients with grade IV osteoarthritis who required surgical treatment, i.e., endorotheses of large joints due to the presence of concomitant diseases. ...