Online ISSN: 2515-8260

Keywords : Obstructive uropathy


Transurethral resection and retrograde ureteral stenting in obstructive uropathy secondary to Carcinoma Cervix-Palliative Rescue from an otherwise doomed existence

Ravikumar Banavase Ramesh, Tejas Chiranjeevi, Manjunath V, Shalini Anand, Amruthraj G Gowda, Madappa KM

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 512-525

Aims and objectives : 1.To determine the impact on quality of life post trans-urethral resection
of ureteric orifice and retrograde DJ stenting in patients with obstructive uropathy secondary to
carcinoma cervix.
2. To compare the outcomes and quality of life of patients who underwent resection and DJ
stenting with patients who underwent PCN insertion using the available literature about PCN.
Materials and methods:- In this study, 40 patients were selected for palliative urinary diversion
by transurethral resection of ureteric orifice and internal drainage using DJ
stenting.77.5%ofpatientspresentedwithobstructive
uropathysecondarytorecurrenceofcarcinomacervix,20%presentedasprimarytumour and 2.5%
presented as VUJ stricture post radiotherapy. 90% had bilateral involvement of the ureteric
orifice and only 10% had unilateral involvement.
Results:- Themeancreatininevalueamong40patientswas4.12mg/dlbeforetransurethralresection
andstenting.62.5%underwenttransurethralresectionofuretericorificeandbilateralDJstentingwhile3
7.5% underwent unilateral DJ stenting. Complete renal recovery was seen in 2 weeks with
creatinine values<1.5mg/d in 72.5%whereasinrestofthe27.5%patients mean creatinine was<
3.0mg/dl.
Conclusion:-
ThetechniqueoftransurethralresectionofuretericorificeandretrogradeDJstentingasapalliative
procedure was able to show better quality of life with respect to physical and mental functioning
in patients with obstructive uropathy secondary to carcinoma cervix. Also the renal recovery
wasgood and comparable to PCN.

Program For Diagnosing The Degree Of Urodynamic Disorders And Kidney Functions And Determining Tactics Of Managing Children With Obstructive Uropathies.

Mavlyanov Farkhod Shavkatovich; Mavlyanov Shavkat Khodzhamkulovich; Shirov Timur Furkatovich; Khayitov Ulugbek Khudzhakulovich

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 2546-2554

Background: The objective of the study is to develop a program of scoring for determining the degree of impairment of urodynamics and the preservation of renal function in children with obstructive uropathy on the basis of data from ultrasound - Doppler studies.
Methods: The work is based on the results of ultrasound and Doppler examination of 484 children with congenital obstructive uropathy. In accordance with the obtained data, a point assessment of the degree of impairment of urodynamics and preservation of renal function was carried out in 60 children with obstructive uropathies (30 children with congenital hydronephrosis and 30 children with congenital ureterohydronephrosis).
Results: Analysis of ultrasound and Doppler studies in congenital obstructive uropathy in children by comparing the data, depending on the severity and level of obstruction, revealed 3 degrees of congenital obstruction of the upper urinary tract in children. A comparative study of the urodynamics and state of the renal parenchyma, depending on the degree of obstruction, established a close relationship between the indicators of the functional state of the renal parenchyma and the degree of dilatation and disorders of the urodynamics of the upper urinary tract.
Conclusion: The developed program allows the safe and most informative methods to reliably determine the functional state of the renal parenchyma and the degree of urodynamic impairment in children with obstructive uropathy. Study Registration (ClinicalTrials.gov) ID NCT04605835.