Online ISSN: 2515-8260

Keywords : Non-alcoholic fatty liver disease

Ultrasonographic Evaluation of Cardiovascular and Fatty Liver Diseases in Type 2 Diabetic Patients: A Prospective and Observational Study

Anshuman Anand

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 6, Pages 1208-1212

Aim: Using ultrasound to examine individuals with type 2 diabetes having fatty liver disease and cardiovascular diseases.
Methods: The prospective and observational study was carried out during a nine-month period in the Radiology Department of the MGM Medical College, Kishanganj, Bihar. A total of 300 patients with type 2 diabetes who had abdominal ultrasonography that revealed no other co-morbid conditions and fatty alterations in the liver were included. According to how long the patients had been diagnosed with diabetes, the patients were separated into three groups. Interview schedule questionnaire, OPD records, bedside tickets, physical examination, and laboratory measures made up the study's methodology.
Results: 145 (48.3%) of the 300 patients were men, and 155 (51.7%) were women. The majority (39%) of the patients were between the ages of 50 and 60, while 25.7% of them were between the ages of 40 and 50. 18.3% of the population was between 60 and 70 years old, 10.7% was under 40, and 6.3% was older than 70. 75 (25%) of the 300 cases had non-fatty liver, while 225 (75%) of the cases had fatty liver. 33.4% (100) of the patients who were included belonged to group A, 40% (120) to group B, and 26.6% (80) to group C. The majority of patients (230, 76.7%) did not show ischemia alterations, however 70 (23.3%) cases out of 300 patients did.
Conclusion: Every patient with newly diagnosed type 2 diabetes should consider having a liver ultrasound because NAFLD is particularly common in this population of patients. It may be claimed that in those with type 2 diabetes, there was a correlation between cardiovascular risk factors and NAFLD.

Clinical profile of non-alcoholic fatty liver disease in type 2 diabetic patients

Dr.Anil Kumar, Dr.Vinay Durgad,Dr.Raghu Nandan

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 454-458

NAFLD may progress through three different stages, from hepatic steatosis to steatohepatitis and finally to cirrhosis. Hepatic steatosis represents simple increase in accumulation of fat in liver, without evidence of inflammation or liver damage. Inflammation and liver damage is however present in steatohepatitis. NAFLD was defined as any degree of fatty liver in the absence of alcohol intake. NAFLD, if present, was classified based on standard ultrasonographic criteria as: Grade 1 (mild steatosis): slightly increased liver echogenicity with normal vessels and absent posterior attenuation. Prevalence of high Waist circumference, which is important marker of central obesity, according to ATP III guidelines for male waist circumference is(≥102 cms) & for female is (≥88 cms) consider as central obesity. In our study,14(58.33%)males patients had waist circumference is ≥102cms &25(96.15%)females patients had waist circumference is ≥88cms. Mean waist cicumference in male were 102.58cms & in female were 96.5cm

Risk Factors For The Progression Of Non-Alcoholic Fatty Liver Disease And The State Of Intestinal Microflora In Overweight And Obese Patients

Botir T. Daminov; Umida Sh. Usmanova; Bahromkhon A. Alavi; Gozal N. Sobirova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 3535-3548

Recently, the growth of non-alcoholic fatty liver disease has been actively discussed in domestic and foreign literature. In Uzbekistan, the incidence of non-alcoholic fatty liver disease increased from 27.0% in 2007 to 37.1% in 2014 and ranked first among liver diseases.