European Journal of Molecular & Clinical Medicine

Abstract

In the development of intravascular thrombosis, aggregation of Platelets, adhesion of platelets play themain role in the development of micro vascular and macro vascular complications with alterations in the morphology of the platelets, function. On analyzing the glycemic control, it was found that the mean HbA1C was very high (10.43%, 95% CI 10.06 to 10.81), which indicates that diabetes was poorly controlled. The lowest recorded HbA1C was 10.15% and the highest recorded value was 15.70%. V Mohan et al (2013)⁽⁶²⁾ published the HbA1C study, which assessed the glycemic status among urban South Indian population. Data from 20,554 patients showed that the mean HbA1c was 9.2%, and diabetes control was worse in those with longer duration of diabetes (9.9 +/- 5.5 years). Other authors from the western countries, including Demirtas L et al (2015) ⁽¹³⁾in their study on 307 diabetic subjects  reported a mean  HbA1C of  8.6  with an IQR of 6.9-10.4 which was much lower. The stark differences in HbA1c may be attributed to the long duration of diabetes, poor compliance of patients to treatment and follow up and associated conditions of healthcare in the rural Indian setting.