ASSESSMENT OF QUALITATIVE COLONIC CANCER OF OVARIAN CANCER ORIGIN.
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 6, Pages 3123-3128
AbstractBackground: Colorectal cancer (CRC) has increased in the last decades, which constitutes about 10% of cancer mortality. In women and men, it becomes the second and third most prevalent cancer.
Objective: To explore the origin and factors for colorectal cancer in Iraq including age, family history, diabetes, smoking, serum carcinembryonic antigen (CEA) as a predictor factor, stages of cancer, bowl habit, and symptoms.
Patients and methods: This study was conducted in surgical unit at Baghdad, during the period from 2003 to 2020. This is a case series study for 736 patients with colorectal cancer. The data gathered included: history of presence ovarian cancer, age, family history, diabetes and smoking, serum CEA, stages of the disease, bowl habit and symptoms. Data are presented as mean and percentage, and were analyzed by using the test of Chi square.
Results: Colorectal cancer patient ages were between 20- 50 years were the higher proportion of patients and were significantly (p ≤ 0.01) higher than the other patients with ≥ 50 years or ≤ 25 years. Female with CRC of ovarian origin (59.5 %) were significantly (p ≤ 0.01) higher than female patients with non ovarian origin (40.5%). Patients with family history were 31.2% of the total patients. Diabetic patients presented at 37.2%. Most of the patients had serum CEA ≥ 5 ng/mL (82.7%) and they were highly significant (p ≤ 0.001) for serum CEA than the patients with less than 5. Stage 2 (42.3%) was significantly higher than stage 1 (15.6%), 3 (21.3%) and 4 (14.5%). For bowl habit, constipation presented 75.7% was significantly higher than diarrhea (24.3%). In addition, symptoms of bleeding per rectum (71.1%) was significantly higher than symptoms of pain was 28.9%.
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