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  2. Volume 8, Issue 3
  3. Authors

Online ISSN: 2515-8260

Volume8, Issue3

Contrast-Induced Nephropathy: a comprehensive review.

    Kamel Hassan Ghazal Tamer Muhammed Moustafa Abdelghany Khaled Muhammed Souliman Hamed Ahmed Said Eldamahoury

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 2169-2180

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Abstract

Contrast-induced nephropathy (CIN) is defined as the impairment of renal function
measured as either a 25% increase in serum creatinine (SCr) from baseline or a 0.5
mg/dL (44 μmol/L) increase in absolute SCr value within 48-72 hours after
intravenous contrast administration. Although prophylactic hydration has been
promising in decreasing the occurrence of CIN, other efforts such as diuretics,
calcium channel blockers, theophylline, aminophylline, atrial natriuretic peptide,
dopamine, and fenoldopam have been disappointing. The preventive effect of Nacetylcysteine
on CIN has not been consistent in the literature. In a recent clinical
trial, bicarbonate infusion was more effective than hydration in the prevention of
CIN. Mechanical devices are in development to perfuse renal arteries with
protective drugs during contrast exposure or for removal of contrast from coronary
sinus during coronary angiography. In this article, we have reviewed available data
in regards to CIN.
Keywords:
    Contrast-induced nephropathy (CIN) is defined as the impairment of renal function measured as either a 25% increase in serum creatinine (SCr)
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(2021). Contrast-Induced Nephropathy: a comprehensive review.. European Journal of Molecular & Clinical Medicine, 8(3), 2169-2180.
Kamel Hassan Ghazal; Tamer Muhammed Moustafa Abdelghany; Khaled Muhammed Souliman Hamed; Ahmed Said Eldamahoury. "Contrast-Induced Nephropathy: a comprehensive review.". European Journal of Molecular & Clinical Medicine, 8, 3, 2021, 2169-2180.
(2021). 'Contrast-Induced Nephropathy: a comprehensive review.', European Journal of Molecular & Clinical Medicine, 8(3), pp. 2169-2180.
Contrast-Induced Nephropathy: a comprehensive review.. European Journal of Molecular & Clinical Medicine, 2021; 8(3): 2169-2180.
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