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  1. Home
  2. Volume 7, Issue 11
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Online ISSN: 2515-8260

Volume7, Issue11

Antioxidant Activity Of Pyrazolopyrimidine Derivatives

    Huma khan Dr. Sudha singh

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 7959-7666

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Abstract

A novel series of substituted pyrazolopyrimidine derivatives have been synthesized from
substituted hydrazine derivatives and ethoxy (methylene) malanonitrile gives an
intermediate (5-amino-1- substituted phenyl pyrazole-4-carbonitrile) (1) which on further
react with formic acid, acetic acid/HCl and formamide gives series of (1-
substitutedphenyl)1H pyrazole [3,4-d] pyrimidine-4(5H)-one (2). The synthesized
compounds were characterized on the basis of IR, 1H NMR and Mass spectral data.
Furthermore, these newly synthesized compounds were screened for their antioxidant
activity by DPPH free radical scavenging method. Unfortunately none of the compound
shows antioxidant activity.
Keywords:
    Pyrazolopyrimidine Antioxidants activity Ascorbic acid
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(2021). Antioxidant Activity Of Pyrazolopyrimidine Derivatives. European Journal of Molecular & Clinical Medicine, 7(11), 7959-7666.
Huma khan; Dr. Sudha singh. "Antioxidant Activity Of Pyrazolopyrimidine Derivatives". European Journal of Molecular & Clinical Medicine, 7, 11, 2021, 7959-7666.
(2021). 'Antioxidant Activity Of Pyrazolopyrimidine Derivatives', European Journal of Molecular & Clinical Medicine, 7(11), pp. 7959-7666.
Antioxidant Activity Of Pyrazolopyrimidine Derivatives. European Journal of Molecular & Clinical Medicine, 2021; 7(11): 7959-7666.
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