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  2. Volume 7, Issue 10
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Online ISSN: 2515-8260

Volume7, Issue10

The Study of clinical and pathological factors of gastric cancer

    Dr. Rajeev Ranjan Kumar , Dr. Seema Kumari , Dr. Binay Kumar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 10, Pages 4031-4038

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Abstract

Aim: to study clinical and pathological factors of gastric cancer in Ranchi region, India.
Material and methods: This study was carried out in the Department of General Surgery, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India, for 3 years (1 july 2012,30 june 2015) Total 650 patients were included in this study.
Results: Of these 650 patients, 460 (70.77%) male and 190 (29.23%)female, 395 (60.77%) underwent distal gastrectomy, 30 (4.62%) proximal gastrectomy via abdomen and 157 (24.15%) via thorax, and 68 (10.46%) underwent total gastrectomy. Distal and total gastrectomy had more numbers of clearances of lymph nodes than the other operational approaches. The postoperative complications occurred in 55 patients 55/600, 8.46%,including gastric retention in 14(14/55, 25.45%), anastomotic leakage in 10(10/55,18.18%), infection of incision in 9(9/55, 16.36%), disruption of wound in 5(5/55, 9.09%), and thoracic cavity effusion in 5(5/55,9.09%). The complication was most common in proximal gastrectomy via abdomen (12/55,21.81%patients). The overall mortality was 0.77% (5/650). The diameter of the neoplasm was positively correlated with the depth of infiltration and lymphatic metastasis rate while hemoglobin was the opposite. 95(14.61%) of 650were early gastric carcinoma (EGC) with metastasis of lymph nodes in 14 patients (14/95, 14.74%). The frequency of positive lymph nodes in these patients was 4%-5% less than in advanced gastric cancer. In linear regression analysis, age and diameter of the tumor were negatively correlated with the preoperative hemoglobin (P<0.001).
Conclusion: This retrospective study has shown that clinico-pathological characters in gastric cancer varied with sex, location, and diameter of the tumor.
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(2021). The Study of clinical and pathological factors of gastric cancer. European Journal of Molecular & Clinical Medicine, 7(10), 4031-4038.
Dr. Rajeev Ranjan Kumar , Dr. Seema Kumari , Dr. Binay Kumar. "The Study of clinical and pathological factors of gastric cancer". European Journal of Molecular & Clinical Medicine, 7, 10, 2021, 4031-4038.
(2021). 'The Study of clinical and pathological factors of gastric cancer', European Journal of Molecular & Clinical Medicine, 7(10), pp. 4031-4038.
The Study of clinical and pathological factors of gastric cancer. European Journal of Molecular & Clinical Medicine, 2021; 7(10): 4031-4038.
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