Document Type : Research Article
Advanced intermittent hypoxia-normoxia KZ-001 (manufactured in Japan under the
Japanese Wellness Science and Technology) is a combination of a fine-tuned
hypobaric (hypoxia) and hyperbaric (hyperoxia) chamber. It is a new Japanese method
that uses both aerospace and high-terrestrial altitude research or training to stimulate
the effects of high altitude on the human body, especially hypoxia and hyperoxia.
This study aimed to test two hypotheses in response to advanced intermittent hypoxianormoxia
KZ-001 stratification based on its mechanism of action and to answer the
following clinical question: Do patients’ glycated hemoglobin (HbA1c) levels decrease
when undergoing advanced intermittent hypoxia-normoxia KZ-001 treatment?