European Journal of Molecular & Clinical Medicine

Abstract

FIESTA (FastImagingEmployingSteady-stateAcquisition) is
commonlyacceptedthatbelongstotheclass of gradient-echosequence (1). FIESTA has
provedto be useful in abdominalimagingformagneticresonansimaging (MRI) of
gastrointestinalsystem, oncologicimagings, assessingvascularpatency. However, FIESTA
MRI findings of fattyliver has not previouslybeenreported, although it
describedthesignalreductionduetofat in previousarticles.
Weobservedthatthepatientswithfattyliver had lowersignalintensity (SI) values at FIESTA
sequencescomparedto normal patientswithoutfattyliver.
Materialsandmethods:
Thirtypatientswithliverfatandthirtypatientswithoutfattyliverwerethecontrolgroup.Thirtypatie
ntswho had detectedfattyliver at T1W in-out of phase MRI (IOP-MRI)
imageswereevaluatedwithcoronalFIESTA sequence at 1.5 Teslascanner.
Allpatientswereobtained FIESTA sequenceusingthesame MRI acqusitionparameters.
LiverandspleenSI’sweremeasured as usingsame ROI on coronal FIESTA
sequencesandlivertospleen SI ratiowerecalculated. Allvalueswerecompared.
Results:
Decrease in SI of thefattyliver on FIESTA images is
negativelycorrelatedwiththefattyfraction of theliver. Patientswithfattyliver had liver / spleen
SI ratiofrom 0.15 to 0.71 (mean 0.39), and 0.41 to 0.96 in thecontrolgroup (mean 0.70).
Therewas a statisticallysignificantdifference.
Conclusion:
Webelievesuggestthatbalancedgradientechosequencesuch as FIESTA, can
detectfattyliverhoweverfurtherstudiesarerequiredforevaluatethecapability of thesequence in
evaluation of fattyfraction of theliver.