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  2. Volume 8, Issue 3
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Online ISSN: 2515-8260

Volume8, Issue3

Role of Prophylactic Antibiotic (Cefotaxime) In Elective Surgical Procedures

    Darshan Jit Singh Walia, Jaswinder Kaur, Manpreet Kaur, Nikhil Dehankar,

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 2616-2629

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Abstract

Introduction: The role of prophylactic antibiotics in elective surgical procedures in preventing surgical site infections has been well documented, however, their need continues to be ambiguous.
Aim: To evaluate the role of prophylactic cefotaxime therapy in the prevention of surgical site infection in elective surgery and its side effects
Materials and Methods: 100 patients undergoing elective surgery were enrolled in the study after taking informed consent. They were divided into two groups of 50 each. Group A patients (control group) did not receive any preoperative, intraoperative or postoperative antibiotics whatsoever, and Group B patients (study group) received a single dose of intravenous cefotaxime half and hour prior to the induction of anaesthesia.  The severity of wound infection was graded according to Robertson’s Classification into grades 0-IV. Culture and sensitivity was done for the presence of pus.
Results: Of the 100 patients in the study, 7% patients developed surgical site infection. However with the administration of prophylactic antibiotics the rate of post-operative infection fell from 7(14%) to 0% (p<0.001). The duration of hospital stay was prolonged in patients that did not receive prophylactic antibiotics.
Conclusion:The use of cefotaxime as a prophylactic antibiotic is a cost effective method in preventing wound infection following clean, elective surgical procedures.
 
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(2021). Role of Prophylactic Antibiotic (Cefotaxime) In Elective Surgical Procedures. European Journal of Molecular & Clinical Medicine, 8(3), 2616-2629.
Darshan Jit Singh Walia, Jaswinder Kaur, Manpreet Kaur, Nikhil Dehankar,. "Role of Prophylactic Antibiotic (Cefotaxime) In Elective Surgical Procedures". European Journal of Molecular & Clinical Medicine, 8, 3, 2021, 2616-2629.
(2021). 'Role of Prophylactic Antibiotic (Cefotaxime) In Elective Surgical Procedures', European Journal of Molecular & Clinical Medicine, 8(3), pp. 2616-2629.
Role of Prophylactic Antibiotic (Cefotaxime) In Elective Surgical Procedures. European Journal of Molecular & Clinical Medicine, 2021; 8(3): 2616-2629.
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