European Journal of Molecular & Clinical Medicine

Abstract

Paracetamol have been extensively used in both the human and veterinary clinics due to its
antipyretic and analgesic properties.It is considered as a well-tolerated drug in patients
suffering from aspirin intolerance, ulcers, or difficulty in blood clotting. It is very important to
monitor the doses of paracetamol in the patient’s body under examination since the overdose
results in accumulation of toxic metabolites which may cause severe adverse effects. Due to a
wide use of paracetamol and the adverse effects of its over dose, it is alwaysbeing an
interesting issue to develop suitable techniques for its quantitative as well as qualitative
analysis. The development of simple, convenient, highly sensitive, versatile, fast and economic
techniques is very necessary to control the over uses of this drug causing many side effects.
Various techniques used for the determination and detection of paracetamol have been
reviewed in this paper predominantly focusing on electro-analytical methods.