• Register
  • Login

European Journal of Molecular & Clinical Medicine

  • Home
  • Browse
    • Current Issue
    • By Issue
    • By Subject
    • Keyword Index
    • Author Index
    • Indexing Databases XML
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Indexing and Abstracting
    • Peer Review Process
    • News
  • Guide for Authors
  • Submit Manuscript
  • Contact Us
Advanced Search

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 2, Issue 3
  3. Authors

Online ISSN: 2515-8260

Volume2, Issue3

Translational medicine and varicella zoster virus: Need for disease modeling

    Aamir Shahzad Don Gilden Randall J. Cohrs

European Journal of Molecular & Clinical Medicine, 2015, Volume 2, Issue 3, Pages 89-91

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

VZV is a ubiquitous human pathogen typically encountered early in life when primary infection causes chickenpox. During this time the virus infects ganglionic neurons at all levels of the neuraxis where the virus remains latent in host neurons. The fact that 495% of the world’s inhabitants have an immunologic response to VZV highlights the problem encountered when ascribing disease etiology to VZV reactivation. There are multiple challenges and problems to better understand pathobiology of VZV latency. There is currently no suitable disease model that mirrors the human diseases caused when virus reactivates. Without a disease model, Koch’s postulates cannot be met and ascribing a causal relationship is tenuous. Without a suitable model for all facets of VZV infection, latency and reactivation, understanding of VZV pathobiology will be difficult. Focal points: Benchside Suitable models for all facets of VZV infection, latency and reactivation are required to better understand the mechanism of VZV pathobiology. Governments Due to the increasing number of geriatric population at risk for severe disease caused by varicella zoster virus reactivation, there is immediate need to increase funding for research studies to find suitable models for VZV infection, latency and reactivation.
Keywords:
    VaricellaZosterVZVvasculopathyeGCAArteritisOgilvier’s syndromeTranslational medicine
  • PDF (180 K)
  • XML
(2015). Translational medicine and varicella zoster virus: Need for disease modeling. European Journal of Molecular & Clinical Medicine, 2(3), 89-91.
Aamir Shahzad; Don Gilden; Randall J. Cohrs. "Translational medicine and varicella zoster virus: Need for disease modeling". European Journal of Molecular & Clinical Medicine, 2, 3, 2015, 89-91.
(2015). 'Translational medicine and varicella zoster virus: Need for disease modeling', European Journal of Molecular & Clinical Medicine, 2(3), pp. 89-91.
Translational medicine and varicella zoster virus: Need for disease modeling. European Journal of Molecular & Clinical Medicine, 2015; 2(3): 89-91.
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 8
  • PDF Download: 14
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
Journal Information

Publisher:

Email:  info@ejmcm.com

  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap

Editorial Team:  editor@ejmcm.com

For Special Issue Proposal : chiefeditor.ejmcm@gmail.com / info@ejmcm.com

This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus