• Register
  • Login

European Journal of Molecular & Clinical Medicine

  1. Home
  2. Urinary biomarkers for the diagnosis of urothelial bladder cancer

Current Issue

By Issue

By Author

By Subject

Author Index

Keyword Index

About Journal

Aims and Scope

Editorial Board

Publication Ethics

Indexing and Abstracting

Related Links

FAQ

Peer Review Process

Journal Metrics

News

Urinary biomarkers for the diagnosis of urothelial bladder cancer

    Authors

    • Douglas G. Ward
    • Jamie J. D'Costa
    • Jamie J. D'Costa
    • Jamie J. D'Costa
    • Richard T. Bryan
    • Jamie J. D'Costa
,
  • Article Information
  • Download
  • Export Citation
  • Statistics
  • Share

Abstract

Urothelial bladder cancer is a common cancer associated with considerable burden for both patients and healthcare providers alike. The majority of patients present with non-muscle-invasive bladder cancer (NMIBC) which, although not immediately life-threatening, requires appropriate initial management and long-term surveillance which is both invasive and costly. Accurate diagnostic urinary biomarkers could be transformational in this setting, yet have proved to be a significant challenge to bladder cancer scientists over the last two decades. Such biomarkers would need to represent a range of tumour grades and stages, encompass inter- and intra-tumour heterogeneity, and compete with the current diagnostic gold standard of cystoscopy with a sensitivity and specificity of 85% and 87%, respectively. For the field to move forward in this current exciting era of high-throughput proteomics and genomics, bladder cancer scientists need to find a consensus on the optimal urinary substrate (DNA, RNA, protein, etc) and deliver robust well-designed studies in the correct populations with appropriate statistical input. Issues relating to tumour heterogeneity and anticipatory diagnosis also require considerable thought. The challenge remains unchanged.

Keywords

  • Bladder cancerUrinary biomarkersDiagnosis
  • XML
  • PDF 337.84 K
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
    • Article View: 107
    • PDF Download: 115
European Journal of Molecular & Clinical Medicine
Volume 3, Issue 5
October 2017
Page 221-223
Files
  • XML
  • PDF 337.84 K
Share
Export Citation
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
Statistics
  • Article View: 107
  • PDF Download: 115

APA

Ward, D. G., D'Costa, J. J., D'Costa, J. J., D'Costa, J. J., Bryan, R. T., & D'Costa, J. J. (2017). Urinary biomarkers for the diagnosis of urothelial bladder cancer. European Journal of Molecular & Clinical Medicine, 3(5), 221-223.

MLA

Douglas G. Ward; Jamie J. D'Costa; Jamie J. D'Costa; Jamie J. D'Costa; Richard T. Bryan; Jamie J. D'Costa. "Urinary biomarkers for the diagnosis of urothelial bladder cancer". European Journal of Molecular & Clinical Medicine, 3, 5, 2017, 221-223.

HARVARD

Ward, D. G., D'Costa, J. J., D'Costa, J. J., D'Costa, J. J., Bryan, R. T., D'Costa, J. J. (2017). 'Urinary biomarkers for the diagnosis of urothelial bladder cancer', European Journal of Molecular & Clinical Medicine, 3(5), pp. 221-223.

VANCOUVER

Ward, D. G., D'Costa, J. J., D'Costa, J. J., D'Costa, J. J., Bryan, R. T., D'Costa, J. J. Urinary biomarkers for the diagnosis of urothelial bladder cancer. European Journal of Molecular & Clinical Medicine, 2017; 3(5): 221-223.

  • Home
  • About Journal
  • Editorial Board
  • Submit Manuscript
  • Contact Us
  • Glossary
  • Sitemap

News

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

Newsletter Subscription

Subscribe to the journal newsletter and receive the latest news and updates

© Journal Management System. Powered by ejournalplus