European Journal of Molecular & Clinical Medicine

Abstract

Ewing sarcoma, along with peripheral primitive neuroectodermal tumour, belongs to a
tumour family that shares clinicopathologic and molecular genetic features, including the
characteristic chromosomal translocation that results in the fusion opf EWS gene on
22q12 to either FLI1 gene on 11q24. In contrast , such translocations are not found in
central primitive neuroectodermal tumours(cPNETs). Ewing sarcoma has only rarely been
noted to primarily involve the central nervous system- extraoseus Ewing sarcoma(CNSESS).
We report a case series of three patients with intracranial extension