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  2. Volume 7, Issue 9
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Online ISSN: 2515-8260

Volume7, Issue9

Study of the functional status of cardiovascular autonomic neuropathy in type 1 diabetic mellitus as compared to healthy individuals

    Snehalata Mali, Charushila Rukadikar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 3736-3742

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Abstract

Background: In the presence of type 1 diabetes mellitus, the incidence of autonomic dysfunction has increased and various evaluation methods have been identified. Each of these is the classical autonomic control tests.
Aims and Objectives: The present study was conducted to evaluate and compare autonomic function tests in cases of type I diabetes mellitus and healthy individuals.
Material and Methods: In the study, 60 cases of diagnosed type I diabetes mellitus and 60 age and sex-matched healthy individuals both between the age group of 18-25 years were included. Autonomic function tests were carried out and these parameters were compared between these two groups using an unpaired t-test.
Results: Deep breathing difference in patients of type I diabetes mellitus was significantly decreased as compared to healthy individuals. Valsalva ratio in patients of type I diabetes was significantly decreased as compared to healthy individuals. Postural tachycardia index in patients of type I diabetes was significantly decreased as compared to healthy individuals. The decrease in systolic blood pressure in patients with type I diabetes was substantially higher than in healthy individuals. The increase in diastolic blood pressure with isometric handgrip monitoring in patients with type I diabetes was substantially lower relative to healthy individuals.
Conclusion:  Deep breathing difference, Valsalva ratio, postural tachycardia index are a measure of parasympathetic function. Deranged autonomic function tests in type I diabetic patients may be due to sympathetic and parasympathetic dysfunction.
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(2021). Study of the functional status of cardiovascular autonomic neuropathy in type 1 diabetic mellitus as compared to healthy individuals. European Journal of Molecular & Clinical Medicine, 7(9), 3736-3742.
Snehalata Mali, Charushila Rukadikar. "Study of the functional status of cardiovascular autonomic neuropathy in type 1 diabetic mellitus as compared to healthy individuals". European Journal of Molecular & Clinical Medicine, 7, 9, 2021, 3736-3742.
(2021). 'Study of the functional status of cardiovascular autonomic neuropathy in type 1 diabetic mellitus as compared to healthy individuals', European Journal of Molecular & Clinical Medicine, 7(9), pp. 3736-3742.
Study of the functional status of cardiovascular autonomic neuropathy in type 1 diabetic mellitus as compared to healthy individuals. European Journal of Molecular & Clinical Medicine, 2021; 7(9): 3736-3742.
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