A prospective study and Correlation between Glycosylated Haemoglobin and Serum Lipid Profile in Patients with Type 2 Diabetes Mellitus in KBN Hospital, Karnataka, India
European Journal of Molecular & Clinical Medicine,
2021, Volume 8, Issue 3, Pages 3153-3160
AbstractIntroduction: Patients with type 2 diabetes have an increased prevalence of lipid abnormalities, contributing to their high risk of cardiovascular diseases (CVD). This study is an attempt to evaluate the diagnostic value of Glycosylated hemoglobin (HbA1c) in predicting diabetic dyslipidemia.
Aims & Objectives: To study the correlation between glycosylated hemoglobin (HbA1c) and serum lipid profile in Type 2 Diabetics
Material and Methods: This is a cross sectional study conducted at Department of General Medicine, Khaja Banda Nawaz University, Kalaburagi,Karnataka from December 2018 to February 2019. In our study 50 patients of Type 2 diabetes mellitus were taken for the study after applying inclusion and exclusion criteria, and after obtaining written and informed consent from them. HbA1c and Fasting Lipid profile were done using appropriate tests. Correlation (Pearson’s) test was used to interpret the result
Results: Mean total cholesterol was 155.76±13.41, mean total triglyceride was 180.52±17.21, mean LDL was 99.09±12.72, Mean HDL was 36.94±4.28 and mean HbA1c was 9.76±1.46. HbA1c negatively and significantly correlated with HDL (r= - 0.13). HbA1c positively and significantly correlated with total cholesterol (r=0.20) and LDL (r=0.24), did not show any show correlation with VLDL (r=0.03) and total triglycerides (r=0.02).
Conclusion: It was concluded from the results of this study that HbA1c can also be used as predictor of dyslipidaemia in Type 2 Diabetics in addition to as a glycaemic control parameter.
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