To determine the major maternal and neonatal outcomes in patients of PLROM: A prospective study
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 8, Pages 5983-5988
AbstractAim: To determine major maternal and neonatal outcomes in patients of PLROM.
Methods: A prospective study was conducted in the Department of obstetrics and gynaecology, VIMS, Pawapuri, Nalanda, Bihar, India, India for 15 months. 100 pregnant women who reported to the labour room with premature rupture of membranes at or after 34 completed weeks to 41 weeks of gestation were analysed for maternal and perinatal outcome.
Results: The rate of maternal morbidity was 25% (25 out of 100), commonest was clinical chorio-amnionitis 10% (10 out of 100) followed by febrile morbidity seen in 8% (8 out of 100). Other maternal morbidities were in the form of wound infection-2%, LRTI-1%, MRP 1%, puerperal sepsis 1%. Perinatal morbidity was seen in 32% of cases. Clinical early onset neonatal infection was the commonest cause for perinatal morbidity noticed in 19% cases. Other perinatal morbidities were birth asphyxia 5%, hyperbilirubinemia 3, congenital pneumonia 1%, congenital malformations 1%, late onset sepsis 1%. Perinatal mortality observed was 2%. Out of 100 newborns of mothers who were having pre-labour premature rupture of membranes at 34-41 weeks’ gestation 66% had birth weight more than 2500 grams, 27% had low birth weight, 7 % had one minute Apgar score less than 7, 48 (48 %) were male and 52 (52%) were female, 20(20 %) had C-Reactive protein positive, out of them 6(6%) were having blood culture growth positive and 16(16%) were having WBC count more than 15,000.
Conclusion: PLROM is an enigmatic condition associated with high risk of maternal and perinatal morbidity and mortality. Major maternal morbidity is chorio-amnionitis (10%). Major perinatal morbidity observed is early onset neonatal infection (19%). Prediction of these morbidities is an important step in the management of infection-associated with PLROM.
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