A REVIEW ONAPPLICATION OF MULTIFUNCTIONAL SPRAY-DRIED EXCIPIENT FOR NEW PRODUCT DEVELOPMENT
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 7, Pages 4909-4922
AbstractA number of changes have been made to the tablet manufacturing process, including the introduction of direct compression and the use of high-speed machines. Due to advanced technologies, there has been an increased demand for developing unique excipient functionalities. Multifunctional excipients make use of their flow and compression properties. Because of its simplicity and cost effectiveness, the direct compression method is a highly preferred method of tablet production. It encourages researchers to conduct more extensive research and analysis in order to develop newer excipients with improved tableting properties. For the introduction of the new class of excipients known as co processed spray dried excipients, a spray drying technique was used in conjunction with extensive use of particle engineering and material sciences. To improve the compressibility and flow properties of poorly compressible drugs, multifunctional excipients are used.
Keywords: Multifunctional excipients, direct compression, co-processing, spray drying
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