European Journal of Molecular & Clinical Medicine

Abstract

Aim: To evaluate the effect of Intravenous dexmedetomidine on depth of anaesthesia in patients undergoing lower segment cesarean section under general anaesthesia.
Methods: This prospective observational study was carried out in the Department of Anaesthesiology, Patna Medical College and Hospital, Patna, Bihar, India for 15 months. We included 80 full term parturients in the age group 18-32 years who were posted for elective cesarean section for different indications under General Anaesthesia. They were divided into 2 groups by sealed enveloped technique to receive 1mcg/kg IV dexmedetomidine 10 minutes before induction (Group A) (n=40) or to not receive dexmedetomidine, control group (Group B) (n=40).
Results: Comparing awareness in both group, in Group A the BIS score was around 47-67 and in Group B BIS score was around 60-86, with statistically significant value of P< 0.05. No statistical difference between both groups in Apgar score (P>0.05).
Conclusion: The loading dose of IV dexmeditomidine 1mcg/kg is effective in aborting awareness without affecting APGAR score.