Study of Effect of Caudal Clonidine on Postoperative Pain and Emergence Agitation in Pediatric Patients.
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 10, Pages 4524-4531
AbstractThe aim of the present study was to study the effect of caudal Clonidine on post operative pain and emergence agitation (EA) given as a single shot caudal epidural as an adjuvant with Bupivacaine 0.25% in pediatric patients posted for infraumblical surgeries.In the present prospective study, 60 children of ASA-I aged 2-7 years with weight less than 20 kg posted for infraumbilical surgical procedures under general anesthesia received injection Bupivacaine 0.25% (0.75ml/kg) + Clonidine 1 mcg/kg caudally. Caudal block was performed after the induction of general anesthesia . Postoperatively patients were observed for analgesia, emergence delirium, need of rescue analgesic, side effects/complications for 24 hours postoperatively. Amongst the 60 patients about 38 , 18 and 4 patients required one, two and three doses of rescue analgesic respectively within 24hours of surgery. Out of all, 3 patients had emergence agitation (EA). None of patient had any side effects/ complications. Addition of Clonidine in a dose of 1mcg/kg to 0.25% Bupivacaine for caudal analgesia significantly prolongs the duration of postoperative analgesia and reduces incidence of EA, without any respiratory or hemodynamic side effects.
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