European Journal of Molecular & Clinical Medicine

Abstract

Background:Atrial fibrillation (AF) is commonly associated with overweight and obesity.
Overweight populations have higher incidence, prevalence, severity, and progression of AF
compared with their normal weight counterparts. Stable weight loss decreases AF burden and
AF recurrence following treatment.Epicardial adipose tissue (EAT) is a small but very
biologically active ectopic fat depot that surrounds the heart. Given its rapid metabolism,
thermogenic capacity, unique transcriptome, secretory profile, and simply measurability,
epicardial fat has drawn increasing attention among researchers attempting to elucidate its
putative role in health and cardiovascular diseases.