European Journal of Molecular & Clinical Medicine

Abstract

Premature ejaculation (PE) is very common disease that affect more than 20% of menand the
most common self-reported male sexual disorder. The two most relevant and evidence-based
definitions of PE are those of International Society for Sexual Medicine (ISSM) and American
Psychiatric Association. Both definitions agree on the chronic aspect of this disorder and the
relatively short time interval between penetration and ejaculation (≤1min), the absence of
voluntary control of ejaculation, and the negative consequences, such as distress in nearly all
vaginal penetrations.