• Register
  • Login

European Journal of Molecular & Clinical Medicine

  1. Home
  2. A comparative study of preserved and preservative-free hydroxypropyl methylcellulose-dextran-containing eyedrops in dry eye disease

Current Issue

By Issue

By Author

By Subject

Author Index

Keyword Index

About Journal

Aims and Scope

Editorial Board

Publication Ethics

Indexing and Abstracting

Related Links

FAQ

Peer Review Process

Journal Metrics

News

A comparative study of preserved and preservative-free hydroxypropyl methylcellulose-dextran-containing eyedrops in dry eye disease

    Author

    • Dr. Laxman Kumar, Dr Pankaj Kumar, Dr Awadhesh Kumar Jha
,

Document Type : Research Article

  • Article Information
  • Download
  • Export Citation
  • Statistics
  • Share

Abstract

Background:Dry eye is a disorder of the tear film which occurs due to tear deficiency or
excessive tear evaporation. The present study compared preserved and preservative-free
hydroxypropyl methylcellulose-dextran-containing eyedrops.
Materials & Methods: 56 patients of dry eyes disease were divided into 2 groups of 28 each.
Group I were prescribed dextran 70, 1 mg/ml and hypromellose, 3 mg/ml hydroxypropyl
methylcellulose (HPMC) and group II 0.3 g HPMC and 0.1 g of dextran 70, with 0.01%
benzalkonium chloride (BAK). The ocular surface disease index (OSDI) questionnaire, tear
break up time (TBUT), corneal and conjunctival staining and Schirmer test were performed.
Results: The mean OSDI score at baseline was 42.6 and 39.4 and at 4 weeks was 32.7 and
28.1 in group I and II respectively, TBUT (sec) at baseline was 7.6 and7.4 and at 4 weeks
was 7.1 and 8.1 in group I and II respectively, conjunctival score at baseline was 6.78 and
7.32 and at 4 weeks was 5.30 and 5.4 in group I and II respectively, corneal score at baseline
was 1.47 and 1.24 and at 4 weeks was 0.52 and 0.41 in group I and II respectively and
schirmer test (mm) at baseline was 6.07 and 6.12 and at 4 weeks was 6.80 and 7.25 in group I
and II respectively. The difference was significant (P< 0.05).
Conclusion: Both preserved and preservative-free hydroxypropyl methylcellulose-dextrancontaining
eyedrops were effective in reducing symptoms of dry eyes disease.

Keywords

  • Dry eyes
  • hydroxypropyl methylcellulose-dextran
  • Schirmer test
  • XML
  • PDF 154.63 K
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
    • Article View: 142
    • PDF Download: 209
European Journal of Molecular & Clinical Medicine
Volume 8, Issue 4
July 2021
Page 1868-1871
Files
  • XML
  • PDF 154.63 K
Share
Export Citation
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
Statistics
  • Article View: 142
  • PDF Download: 209

APA

Jha, D. L. K. D. P. K. D. A. K. (2021). A comparative study of preserved and preservative-free hydroxypropyl methylcellulose-dextran-containing eyedrops in dry eye disease. European Journal of Molecular & Clinical Medicine, 8(4), 1868-1871.

MLA

Dr. Laxman Kumar, Dr Pankaj Kumar, Dr Awadhesh Kumar Jha. "A comparative study of preserved and preservative-free hydroxypropyl methylcellulose-dextran-containing eyedrops in dry eye disease". European Journal of Molecular & Clinical Medicine, 8, 4, 2021, 1868-1871.

HARVARD

Jha, D. L. K. D. P. K. D. A. K. (2021). 'A comparative study of preserved and preservative-free hydroxypropyl methylcellulose-dextran-containing eyedrops in dry eye disease', European Journal of Molecular & Clinical Medicine, 8(4), pp. 1868-1871.

VANCOUVER

Jha, D. L. K. D. P. K. D. A. K. A comparative study of preserved and preservative-free hydroxypropyl methylcellulose-dextran-containing eyedrops in dry eye disease. European Journal of Molecular & Clinical Medicine, 2021; 8(4): 1868-1871.

  • Home
  • About Journal
  • Editorial Board
  • Submit Manuscript
  • Contact Us
  • Glossary
  • Sitemap

News

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

Newsletter Subscription

Subscribe to the journal newsletter and receive the latest news and updates

© Journal Management System. Powered by ejournalplus