A Study of Lipid Profile Abnormalities in Rheumatoid Arthritis and its Relation with Disease Activity
European Journal of Molecular & Clinical Medicine,
2021, Volume 8, Issue 4, Pages 2229-2235
AbstractBackground: Rheumatoidarthritis(RA)isachronicsystemicdiseaseaffecting primarily the synovium, leading to joint damage and bone destruction1RAcausessignificantmorbidityasaresultofsynovialinflammation,jointdestruction and associated disability 2. Epidemiological studies have shown anincreased premature mortality in patients with RA compared with the generalpopulation.SeveralinvestigatorsreportedanexcessofcardiovascularmorbidityandmortalityamongRApatients.
Material and methods: This is cross sectional study, total 50 Patients attendingRheumatologyoutpatientdepartment of General medicine, at Darbhanga medical college and Hospital, Laheriasarai, Darbhanga. Duration period of two years.
Conclusion: Patients with Rheumatoid arthritis had significantly reduced levels of serumtotalcholesterol,LDL-cholesterol,triglyceride,ascomparedtocontrols. HDL-cholesterol level was not significantly altered in Rheumatoid arthritis ascomparedtocontrols.
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