European Journal of Molecular & Clinical Medicine

Abstract

Alcoholism represents one of the most serious worldwide socio economic health problems. It is one of the leading cause of preventable mortality, second only to cigarette smoking. Multiple organs can be involved like Hepatobiliary system, cardiovascular system, Central nervous system, Haematopoietic system. Alcohol consumption has been steadily increasing all over world, especially in India. Alcohol can cause physical, mental and social effects which is determined by quantity and pattern of alcohol drinking. Present study was conducted to observe alterations in the liver function parameters in alcohol consumers. Twenty-five adult patients who are moderate alcoholics, 25 patients who are severe alcoholics, and 25 adult patients who are non-alcoholics were selected. Following Liver function test parameters, information of all subjects under the study was collected, Total Bilirubin , Direct bilirubin, Total Protein, Albumin, SGOT, SGPT, ALP. These parameters were compared between alcoholic and non-alcoholic subjects. Total bilirubin , SGOT,SGPT,ALP were increased in Alcoholics as compared to non alcoholics and it was statistically highly significant. There was fall in concentration of the total protein and albumin level in the alcoholics. Liver function test parameters are essential to assess and understand the effect of alcohol on the liver in alcoholics.