A comparative study of topical amorolfine, sertaconazole and terbinafine in patients with tineacorporis and tineacruris
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 1, Pages 74-78
Abstractcommon infection. The disease is caused by dermatophytes belonging to genera of
Trichophyton, Microsporum and Epidermatophyton. The present study was conducted
to compare topical amorolfine, sertaconazole and terbinafine in patients with tinea
corporis and tinea cruris.
Materials & Methods: 90 patients with tinea corporis and tinea cruris of both genders
were included. Patients were divided into 3 groups of 30 each. Group I were prescribed
topical application of amorolfine (0.25%) once daily, group II were given sertaconazole
(2%) twice daily and group III were given terbinafine (1%) twice daily. Response to
treatment was assessed after 3 weeks.
Results: Group I had 14 males and 16 females, group II had 17 males and 13 females
and group III had 12 males and 18 females. The mean value of scaling was 0.92 in group
I, 1.14 in group II and 0.78 in group III. The mean value of erythema was 0.94 in group
I, 1.42 in group II and 0.56 in group III. The mean value of pruritus was 1.12 in group I,
1.32 in group II and 0.65 in group III. The response was poor seen in 42% in group I,
22% in group II and 44% in group III. Moderate seen in 40% in group I, 46% in group
II and 48% I group III and good seen in 18% in group I, 32% in group II and 8% in
group III. The difference was non- significant (P> 0.05).
Conclusion: Sertaconazole found to be effective as compared to other agents in
management of cases of tinea corporis and tinea cruris.
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