European Journal of Molecular & Clinical Medicine

Abstract

Many methods have been evolved to combat wound infection during last century. Shortly
after the introduction of the first antimicrobial agent Penicillin alone was shown to reduce the
infection rate in abdominal surgery to 10% from a control rate of 25%.Initially, the antibiotics
were only used post-operatively for treatment of already established SSI. Later, the concept
of antibiotic prophylaxis was introduced. Many studies established the fact that preoperative
prophylaxis with antibiotics reduces wound infection. All patients were given spinal
anaesthesia all patients were painted with 10%povidone and recleaningwith spirit Surgical
field was drappedproperly and aseptic precautions followed group a: prophylaxis by
preoperative intraincisional infiltration of the antibiotic. One gram of cefotaxime diluted in 10
ml of distilled water will be infiltrated along the skin and the subcutaneous tissue in the
proposed line of incision, 20 minutes before surgical incision. In Group 1, wound discharge
was present in 1% on day 5. In group 2, wound discharge was present in 2% on day 5. There
was no significant difference in wound discharge between two groups. At other intervals
there was no discharge in both the groups.