European Journal of Molecular & Clinical Medicine

Abstract

Background: Diabetes mellitus has a high prevalence globally with rising incidence in the
world. Despite the identification of diabetes mellitus and associated complications for a long
time, the measures to reduce mortality and morbidity in subjects with diabetes mellitus are
focused only for a few decades.
Objective: The present study was conducted to assess the correlation between levels of
glycosylated Hb and serum albumin in subjects with type 2 diabetes mellitus.
Method: The present institution-based observational study included subjects with a
confirmed diagnosis of diabetes mellitus type 2 where levels of glycosylated hemoglobin
(HbA1c) and serum albumin were assessed and correlated.
Result: It was seen that in subjects with glycosylated hemoglobin of <7%, mean serum
albumin level was 3.87±0.88 mg/dl, in subjects with glycosylated hemoglobin of 7-9%, mean
serum albumin level was 2.95±0.53 mg/dl, and in subjects with hemoglobin of >9%, it was
seen that mean serum albumin was 2.46±0.69 mg/dl. A negative correlation was noted where
lesser HbA1C% was related to higher mean values of serum albumin.
Conclusion: The present study concludes that subjects having higher values of glycosylated
hemoglobin have lower serum albumin levels compared to subjects where lower glycosylated
hemoglobin levels in subjects were associated with near-normal or normal serum albumin
levels.