European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Tumors of ovary have an amazingly diverse pathology, the variety being more
than other organ. Owing to their large number and difficulty in diagnosing them at an early
stage, we have chosen to study theSurface epithelial tumors which account for 2/3rd of all
ovarian neoplasm.
Aim: The aim of the study was to determine the incidence of Surface epithelial tumors of
ovary amongst all ovarian tumors received and to assess their clinical presentation, gross and
histomorphological features.
Materials and Methods: This study is a retrospective study of 100 cases of surface epithelial
tumors diagnosed in the department of pathology over a period of 2 years in a tertiary care
center. Detailed clinical data was reviewed.Grossing was done as per standard grossing
protocols. Tissues were processed routinely and stained with Haematoxylin and eosin (H&E)
stained. Special stains and IHC (Immunohistochemistry)was done wherever required. Final
histological diagnosis was given as per WHO classification of ovarian tumors (2014).
Results: Surface epithelial ovarian tumors accounted for 71.43% of primary ovarian tumors of
which 83% were benign, 8% were borderline, and 9% were malignant. The commonest
symptoms were pain in abdomen, abdominal lump, and menstrual abnormality. The
commonest surface epithelial tumor was Serous tumor(57%) followed by Mucinous tumor
(38%), Brenner tumor (2%), Seromucinous tumor (2%), endometrioid tumor (1%). Bilaterality
was seen in only 2% of cases and both were diagnosed as Serous carcinoma. Metastasis was
seen in 2 cases, both of them were high grade Serous carcinoma.
Conclusion: The panorama of ovarian neoplasm is vast, diverse and complex. As concepts
change, newer entities are published and criteria are better defined. To conclude we
recommend histopathological examination of every ovarian mass as pre-operative imaging
modalities like ultrasonography and gross morphology of tumors is not definitive. Targeted
therapy depending on the type of tumor is essential to improve outcome in cases of ovarian
tumors emphasizing the need for histopathological examination and grading in every case of
ovarian tumor.