Comparative study of serum magnesium levels between low dose mgso4and Pritchard regimen in treatment of eclampsia
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 1, Pages 736-741
Abstract
tonicclonicconvulsionsunrelatedtoothermedicalconditionsinwomenwithhypertensivedisorderofpregnancy.Although10%ofpregnanciesarecomplicatedbyhypertensivedisorders,eclampsia
continuesto occur in 0.8% of women with hypertensivedisorders.
Objectives:TocomparetheserummagnesiumlevelsinPritchardregimenandlowdose
MgSO4regimen. To compare the maternaland fetalcomplicationsin both groups.
MaterialandMethods:ThisisaProspectivestudyconductedintheDepartmentofObstetrics
andGynaecologyatTertiarycareteachinghospitaloveraperiodof1yearoneclampticpatients
whogotadmittedindepartmentofobstetricsandgynecology.Standardprinciplesof
managementofeclampsiawillbefollowed.Patientsaredividedintotwogroupsascases&
controlalternatively.Groupsarechosenbasedoninclusion&exclusioncriteria.GroupI
ControlwillfollowPritchardstandardregimen.GroupIICaseswillreceivelowdose
magnesiumsulphateregimen.
Conclusion:Theoccurrenceofeclampsiaintwogroupswasmorecommonintheagerange of 20 to
26yearsamongtheprimigravidaand with previoushistory ofPIH. Thereisnomajor
differenceintheoutcomeofmaternalandfetalinbothgroups.Nonethelessthemagnesium
levelsamonglowdosegrouparesignificantlylowerincomparisonwithstandardregimen group. In
casesand controlsthe magnesium levelsare maintained in normal therapeuticrange.
Lowdoseregimenisbetter alternative tocontrolseizuresin eclampticpatients.
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