• Register
  • Login

European Journal of Molecular & Clinical Medicine

  1. Home
  2. To study the normal values of citrate in urine: A population based study

Current Issue

By Issue

By Author

By Subject

Author Index

Keyword Index

About Journal

Aims and Scope

Editorial Board

Publication Ethics

Indexing and Abstracting

Related Links

FAQ

Peer Review Process

Journal Metrics

News

To study the normal values of citrate in urine: A population based study

    Author

    • Dr. Shiv Shankar Sharma, Dr. Nachiket Vyas, Dr. Shivam Priyadarshi, Dr. Anwar Ali
,

Document Type : Research Article

  • Article Information
  • Download
  • Export Citation
  • Statistics
  • Share

Abstract

A by the enzyme citrate synthase.1, 2 Citrate is thought to be freely filterable at the
glomerulurs, in humans, 65 to 90% of the filtered citrate is reabsorbed and 10 to 35% is
excreted in the urine as a byproduct of oxidative pathways in the body.3, 4 It is known to
inhibit precipitation of calcium oxalate and phosphate and growth of their crystals5.
In 1990 Pak has defined normal 24 hour urinary citrates as more than 320 mg for both
genders6. Hypocitraturia is defined as urinary citrate excretion lower than 1.67 mmol
(320mg) per day. However, there are some reports of low urinary citrate output in stone
formers (SF) and renal failure as compared with healthy subjects7-9, while other studies found
no differences10,11.
Prevalence of hypocitraturia varies widely from 8% to 68.3% in patients with renal
stones.6 Furthermore; there are some differences in the range of 24-hour urinary citrate
excretion in normal subjects.10, 12
Urinary pH is also an important factor in stone risk, with higher values favoring
calcium phosphate stones and lower ones uric acid stones13. Although final urine pH is
associated with acid load, it is also influenced by ammonium excretion and the ability of
the distal tubule to acidify the collecting duct. Overall factors that influence urine pH and
citrate are similar, but not identical.
Various studies have evaluated the citrate levels and have conflicted results. Most of the
studies have been done in stone former patients and very limited studies have been done
in normal Indian population. In this study we intend to find out the normal range of citrate
excretion in normal subjects and its relation with various factors.

  • XML
  • PDF 200.15 K
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
    • Article View: 71
    • PDF Download: 121
European Journal of Molecular & Clinical Medicine
Volume 9, Issue 1
January 2022
Page 797-803
Files
  • XML
  • PDF 200.15 K
Share
Export Citation
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
Statistics
  • Article View: 71
  • PDF Download: 121

APA

Ali, D. S. S. S. D. N. V. D. S. P. D. A. (2022). To study the normal values of citrate in urine: A population based study. European Journal of Molecular & Clinical Medicine, 9(1), 797-803.

MLA

Dr. Shiv Shankar Sharma, Dr. Nachiket Vyas, Dr. Shivam Priyadarshi, Dr. Anwar Ali. "To study the normal values of citrate in urine: A population based study". European Journal of Molecular & Clinical Medicine, 9, 1, 2022, 797-803.

HARVARD

Ali, D. S. S. S. D. N. V. D. S. P. D. A. (2022). 'To study the normal values of citrate in urine: A population based study', European Journal of Molecular & Clinical Medicine, 9(1), pp. 797-803.

VANCOUVER

Ali, D. S. S. S. D. N. V. D. S. P. D. A. To study the normal values of citrate in urine: A population based study. European Journal of Molecular & Clinical Medicine, 2022; 9(1): 797-803.

  • Home
  • About Journal
  • Editorial Board
  • Submit Manuscript
  • Contact Us
  • Glossary
  • Sitemap

News

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

Newsletter Subscription

Subscribe to the journal newsletter and receive the latest news and updates

© Journal Management System. Powered by ejournalplus