European Journal of Molecular & Clinical Medicine

Abstract

Background: In the skin, under influence of ultraviolet radiation, 7-dehydrocholesterol is
photoconverted to provitamin D3, which is converted to Vitamin D3 (cholecalciferol). In the
serum, bound to a Vitamin D binding protein (VDBP), Vitamin D3 is transported to the liver,
where it is hydroxylated to 25(OH)D3. In the kidneys, 25(OH)D3 is further metabolized to
1α,25-dihydroxy vitamin D3 [1,25(OH)D3], the biologically active form of Vitamin
D.Vitamin D (Cholecalciferol) is known to contribute to muscular function.
Material and Methods: In this comparative study, Two groups were formed, First group as a
case in which vitamin D was supplemented and second group as control in which Vitamin D
was not supplemented, both the group had 25 number of post- menopausal women who had
Vitamin D level between sufficient range (30-100ng/ml) and were treated with same mode of
treatment (closed reduction and Percutaneous K-wire fixation) for Distal end radius fracture.
Grip strength recovery (in %) was compared in both the group after a period of 6 months.
Results: Final grip strength recovery of all patients came out to be 67%, out of which, in
supplemented group it came out to be 73% while in non-supplemented group came out to be
60% with p value of statistically significance proving major difference in grip strength
recovery in % at 6 months in both the groups.
Conclusion:We concluded with our series that vitamin D supplementation significantly helps
in improving the grip strength recovery in Post-menopausal women after a Distal End Radius
fracture.