European Journal of Molecular & Clinical Medicine

Abstract

Aim:To assess some quantitative spectral Doppler parameters, resistivity index (RI) and
acceleration time (AT) together to show their reliability for differential diagnosis of
parenchymal thyroid diseases.
Methods: This study was conducted in the Department of Radiology, Maharishi
Markandeshwar University, Solanfor the period of 1 year. Patientsweredivided into five
groups such as group I (normal); group II had first detected, early untreated Hashimoto
disease(EH);groupIII comprised of chronic Hashimoto patients that are under treatment
and/or follow up (H); group IV had multinodular parenchymal hyperplasia (M) and group V
had nodular hyperplasia with Hashimoto (HM). They underwent spectral Dopplerultrasound
usingPhilipsAfiniti 70 G machine by a linear 5-12 MHz probe. Quantitative spectral Doppler
parameters such as resistivity index (RI) and acceleration time (AT) were recorded.
Results: Out of 200, 62.5% were female and 37.5% male most of the patients between 30-40
years 42.5% and followed by 40-50 years was 30%. The distribution of patients was done
based on diseases. The mean RI in group I was 0.57, in group II was 0.60, in group III was
0.45, in group IV was 0.51 and in group V was 0.53. Mean AT in group I was 25.9, in group
II was 24.8, in group III was 69.5, in group IV was 45.8 and in group V was 44.5.The
difference was significant (P< 0.05).
Conclusion: The resistivity index and acceleration time together are reliable for differential
diagnosis of parenchymal thyroid diseases.