European Journal of Molecular & Clinical Medicine

Abstract

Background: Better understanding of the clinical characteristics of Hemolytic Disease of the Newborn due to ABO incompatibility helps to optimise care. ABO incompatibility is complex because anti-A and anti-B antibodies are composed mainly of Immunoglobulin M.
Material and methods: This is  cross sectional study conducted in the neonatal unit of narayan medical college and Hospital Jamuhar Sasaram Rohtas. A total of 50 neonates with blood group A or B born to mothers with blood group O; with jaundice and or anemia were enrolled during the Study period of two years, The various maternal and neonatal parameters and their association with development of jaundice and or anemia was studied. Conclusion: Early identification of high risk neonates with ABO Incompatibility, diagnosis and early intervention can reduce morbidity and mortality.