European Journal of Molecular & Clinical Medicine

Abstract

Background: Present clinical study was conducted to study the effects of intravenous Magnesiun Sulphate on spinal anesthesia with Bupivacaine and Buprenorphine,
Methods:  After thorough pre anaesthetic evaluation , Pre operative vitals para meters in the form of baseline pulse, blood pressure pulse were recorded. A good venous access was taken. Patient connected to ecg, pulse oximetry, non invasive blood pressure monitoring. Patients randomly allocated into two groups: Group M-50 received 50mg/kg intravenous MgSO₄ in 500ml Ringer lactate over 20 mins. Group C-50 received intravenous 500ml Ringer lactate over 20 mins. Both the groups received intrathecal 15mg of Inj.Bupivacaine (0.5%) and 30 mcg of Inj. Buprenorphine.
Conclusion: We conclude that IV bolus dose of magnesium sulfate of 50mg⋅kg−1 in 500mL of Ringer Lactate solution dose not prolongs the duration of anaesthesia and analgesia when given in combination with intrathecal bupivacaine5% and Buprenorphine 30mcg. but it reduces the analgesic consumption and incidence of nausea and vomiting associated with intrathecal Buprenorphine.