Clinical profile and evaluation of level of dependence of alcohol in patients of alcoholic liver disease
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 2, Pages 204-208
AbstractIntroduction: In India, there is a high frequency of ALD, with alcohol being responsible for roughly
half of all instances of cirrhosis. However, not everyone who consumes alcohol develops the condition,
and the total chance of acquiring the disease in a person is determined by a number of variables. The
length, amount, and kind of alcohol ingested, as well as nutritional state, comorbid illnesses, sex, race,
and hereditary variables, may all have a role. Multiple investigations on the impact of drinking patterns
in the development of illness have shown conflicting conclusions.
Objectives: Present study aims towards analysing the clinical profile of patients with alcoholic liver
disease. Present study also aims to perform psychiatric screening using CAGE criteria and alcohol use
disorder identification test (AUDIT) scale for assessing the severity of alcohol dependence.
Methods: Present study was a single centric, prospective, observational and hospital-based study. 50
patients with clinical/investigational evidence of alcoholic liver disease were include in study. CAGE
Criteria to screen and alcohol use disorder identification test (AUDIT) scale was used for assessing the
severity of alcohol dependence.
Results: The mean age of the recruited patients was 50.80 ± 12.74 years. Among total 50 patients, 96%
patients were males and 4% of patients were females. Total 26% patients have CAGE score of four, 34%
patients have CAGE score of three, 40% patients have CAGE score of two whereas no patient had a
CAGE score of zero. AUDIT scoring indicate that 96% patients exhibit alcohol dependence, 4% patients
presented with harmful or hazardous drinking levels whereas no patient presented with Low-risk
consumption. A total of 96% patients were alive whereas mortality occurs in 4% patients in present study.
Conclusion: Our findings show a link between the type, amount, and duration of alcohol consumption
and the development of alcoholic liver disease.
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