European Journal of Molecular & Clinical Medicine

Abstract

Background:Allergic Rhinitis is a common and major chronic respiratory disease due
to its prevalence, impact on the quality of life, impact on school performance and
productivity, economic burden and its strong link with the Asthma. In recent years the
increase in prevalence of Allergic diseases has been found to be associated with low
serum vitamin D levels. A relationship has been seen between vitamin D deficiency and
Allergic Rhinitis and Asthma.
Aim and objective:This study aims to evaluate vitamin D levels in Allergic Rhinitis cases
and controls.
Materials and Methods:The study was carried out in the Department of Physiology at
Index Medical College, Indore, Madhya Pradesh. The study was done on 80 males and
female subjects of the age group 6 to 18 years. Forty males and females suffering from
Allergic Rhinitis attending Ear, Nose and Throat out-patient department of the Index
medical college hospital and research Centre Indore, were taken as cases. Forty healthy
males and females was taken as controls after careful selection as per inclusion and
exclusion criteria, “Vitamin D” estimation was done by ECLIA method (Electrochemi-
Luminescence Immunoassay using Beckmen’s commercial kit).
Results:The Vitamin D levels were significantly lower in Allergic Rhinitis cases
(P<0.001) as compared controls (P<0.000)
Conclusion:Theresults of the present study indicate that vitamin D levels are decreased
in Allergic Rhinitis cases as compared to the controls. Vitamin D deficiency increases
the risk of Allergic Rhinitis.