• Register
  • Login

European Journal of Molecular & Clinical Medicine

  • Home
  • Browse
    • Current Issue
    • By Issue
    • By Subject
    • Keyword Index
    • Author Index
    • Indexing Databases XML
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Indexing and Abstracting
    • Peer Review Process
    • News
  • Guide for Authors
  • Submit Manuscript
  • Contact Us
Advanced Search

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 9, Issue 3
  3. Author

Online ISSN: 2515-8260

Volume9, Issue3

Correlation Analysis of Anaemia with TSH Level and Anti-TPO Expression in Anti-TPO Positive Hypothyroid Patients

    Bhawna Sandhir, Sumeet Chadha, Gagan Sandhir, Rajesh Kashyap, Suraj Bisht, Neeraj Joshi, Jagdeep Singh

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 176-181

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Introduction: Elevated anti-thyroid peroxidase (Anti-TPO) antibodies and thyroid
stimulating hormone (TSH) levels in hypothyroidism have been linked to the alter the
vitamin B12 metabolic pathway thereby imparting the anemia. Thyroid peroxidase is
an important enzyme responsible during organification of iodide for synthesis of
thyroid hormone. Antibodies to TPO are formed as a part of autoimmune response of
body causing autoimmune thyroiditis in patients. Antibodies to thyroid peroxidase
(TPO) are clinically useful markers of thyroid autoimmunity
Objectives: Present study aims to correlate the thyroid stimulating hormone and antithyroid
peroxidase expression in Anti-TPO positive patients with the anemia.
Methods:60 patients who were anti-TPO positive and hypothyroid were recruited in
present study.TSH level, anti-TPO antibodies level and haemogram was analysed
among all patients.
Results: There was a positive correlation between the haemoglobin and TSH level (r=
0.09580). There was a negative correlation between the Haemoglobin and Anti-TPO
expression (r= -0.2086).
Conclusion: Present study revealed a correlation of anemia with TSH level and Anti-
TPO expression which have the diagnostic value. Anti-TPO positive hypothyroid
patients have risk of developing anaemia.
Keywords:
    Anemia TSH Anti-TPO thyroid
  • PDF (125 K)
  • XML
(2022). Correlation Analysis of Anaemia with TSH Level and Anti-TPO Expression in Anti-TPO Positive Hypothyroid Patients. European Journal of Molecular & Clinical Medicine, 9(3), 176-181.
Bhawna Sandhir, Sumeet Chadha, Gagan Sandhir, Rajesh Kashyap, Suraj Bisht, Neeraj Joshi, Jagdeep Singh. "Correlation Analysis of Anaemia with TSH Level and Anti-TPO Expression in Anti-TPO Positive Hypothyroid Patients". European Journal of Molecular & Clinical Medicine, 9, 3, 2022, 176-181.
(2022). 'Correlation Analysis of Anaemia with TSH Level and Anti-TPO Expression in Anti-TPO Positive Hypothyroid Patients', European Journal of Molecular & Clinical Medicine, 9(3), pp. 176-181.
Correlation Analysis of Anaemia with TSH Level and Anti-TPO Expression in Anti-TPO Positive Hypothyroid Patients. European Journal of Molecular & Clinical Medicine, 2022; 9(3): 176-181.
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 134
  • PDF Download: 222
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
Journal Information

Publisher:

Email:  editor.ejmcm21@gmail.com

  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus