European Journal of Molecular & Clinical Medicine

Abstract

Background: Preeclampsia is considered a systemic syndrome of pregnancy and may show hepatic and renal involvement. Serum electrolytes play important role in development of hypertention.
Objective: To study serum electrolytes and biochemical parameters under liver function tests and renal function tests of pre-eclampsia patients in comparison to normal pregnant women.
Method: A case control study was conducted during one year, on 50 cases of pre-eclampsia and 50 controls who were normotensive pregnant females. Their demographic and clinical details were obtained and laboratory analysis of serum electrolytes, liver function tests and renal function tests was done.
Observations: Serum sodium, potassium, calcium, chloride, bicarbonate, Albumin, total protein levels and Aspartate aminotransferase levels were significantly lower in pre-eclampsia cases than in normotensive controls. Alanine Transaminase, Alkaline phosphatase and Uric acid levels were significantly higher in cases of pre-eclampsia as compared to controls.
Conclusion: Close monitoring of pre- eclampsia patients is must as it has deleterious effect on liver and kidney along with electrolytes which may increase maternal and fetal morbidity and mortality.