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A Prospective Study Evaluating Correlation Between Preoperative Histopathology And Morphologywith Recurrence Of PterygiumAfter CLAU Surgery

    Author

    • Dr. Neetu Kori Shankhwar, Dr. Shweta Walia, Dr. DivyaKhandelwal, Dr. V. Bhaisare, Dr. Preeti Rawat, Dr. Manushree Sharma
,

Document Type : Research Article

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Abstract

Aim- To observe recurrence rate after conjunctival limbal autograft (CLAU) and tocorrelate
this with preoperative histopathological and morphologicalcharacteristics of pterygium.
Design: Interventional, Prospective, Hospital-Based Study.
Methods: 107 patients with primary pterygium were examined, managed by CLAU and
histopathology sample sent. The outcomes were assessed in terms of clinically significant or
insignificant recurrence till 6 months follow-up.
Results: 57% patients were female. 17.8% participants had Stockers Line and all patients
having stocker’s line had stationary type of pterygium. Fuchs spots were seen in 4.7% of
patients. Histopathology findings includeEpithelial Hyperplasia (80.4%), Vascularity
Overwhelms Fibrosis (39.1%), Vascularity Similar to Fibrosis (28.3%), Fibrosis Overwhelms
Vascularity (34.8%), Perivascular Stromal Inflammation (54.3%), Diffuse Stromal
Inflammation (37.0%). The following variables were significantly associated (p<0.05) with
the Recurrence: Age, Fuchs Spots, higher vascularity and Diffuse Stromal Inflammation on
histopathology.
Conclusion: Factors such as younger age group,higher redness and thickness of pterygium,
Fuchs Spots, higher vascularity and diffuseinflammation on histopathological examination
can be considered as a risk factor for recurrence. However, occupation, laterality, location
and type of pterygiumwere found not to be related to recurrence.

Keywords

  • Recurrence
  • Pterygium
  • Conjunctivallimbalautograft
  • histopathology
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European Journal of Molecular & Clinical Medicine
Volume 9, Issue 3
February 2022
Page 317-323
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  • Article View: 152
  • PDF Download: 170

APA

Dr. Manushree Sharma, D. N. K. S. D. S. W. D. D. D. V. B. D. P. R. (2022). A Prospective Study Evaluating Correlation Between Preoperative Histopathology And Morphologywith Recurrence Of PterygiumAfter CLAU Surgery. European Journal of Molecular & Clinical Medicine, 9(3), 317-323.

MLA

Dr. Neetu Kori Shankhwar, Dr. Shweta Walia, Dr. DivyaKhandelwal, Dr. V. Bhaisare, Dr. Preeti Rawat, Dr. Manushree Sharma. "A Prospective Study Evaluating Correlation Between Preoperative Histopathology And Morphologywith Recurrence Of PterygiumAfter CLAU Surgery". European Journal of Molecular & Clinical Medicine, 9, 3, 2022, 317-323.

HARVARD

Dr. Manushree Sharma, D. N. K. S. D. S. W. D. D. D. V. B. D. P. R. (2022). 'A Prospective Study Evaluating Correlation Between Preoperative Histopathology And Morphologywith Recurrence Of PterygiumAfter CLAU Surgery', European Journal of Molecular & Clinical Medicine, 9(3), pp. 317-323.

VANCOUVER

Dr. Manushree Sharma, D. N. K. S. D. S. W. D. D. D. V. B. D. P. R. A Prospective Study Evaluating Correlation Between Preoperative Histopathology And Morphologywith Recurrence Of PterygiumAfter CLAU Surgery. European Journal of Molecular & Clinical Medicine, 2022; 9(3): 317-323.

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