European Journal of Molecular & Clinical Medicine

Abstract

Introduction:. The present study was conducted with an aim to assess the role of MRI for evaluation of adnexal masses and to find out the diagnostic accuracy of MRI in the diagnosis of adnexal masses against the gold standard test ‘histopathology’.
Materials and Methods: This is a prospective comparative study conducted in the Department of Radio Diagnosis, Index medical college hospital and research centre.50 women were taken in our study. These patients were first referred for ultrasonography with history of adnexal masses from gynaecological department. The magnetic resonance imaging was done using 1.5 Tesla MRI machine with patient in supine position.Then the lesion sample was taken and sent for histopathological examination. The results obtained on the MRI were evaluated against the histopathology results and the sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of MRI was calculated.
Results: Out of 50 patients, 33 (66%) adnexal masses were benign, 15 (30%) were malignant and 2 (4%) were inconclusive on ultrasonography, 35 (70%) adnexal masses were benign, 15 (30%) were malignant on magnetic resonance imaging. 37 (74%) adnexal masses were benign, 13 (26%) were malignant on histopathology. The sensitivity of MRI in the diagnosis of malignant / benign adnexal masses against the histopathology was found to be 92.31%, specificity was 91.89%, positive predictive value was 80.00%, negative predictive value was 97.14% and diagnostic accuracy was 92.00%.
Conclusion: Ultrasound is unable to differentiate adnexal masses into malignant and benign in some cases and gives inconclusive results. While MRI provides better spatial and contrast resolution in delineation of the anatomical structures as well as characterization of pathological lesions. It is highly accurate in identifying the origin of a mass, characterization and staging and helps in the treatment planning. These parameters have been found quite in agreement with the findings of histopathology