European Journal of Molecular & Clinical Medicine

Abstract

BACKGROUND: -
                         Acne Vulgaris is an extremely common disorder.More than ninety percent of the patients with acne vulgaris suffer scarring leading topsychological impact and cosmetic disfigurement after healing of their acne lesions.Atrophic acne scars are more common and difficult to treat .These can be sub-classified into icepick, rolling and box car depending on their width, depth and shape. Microneedling device performs acne scar remodelling via collagen induction therapy. Autologous platelet-rich plasma therapy combined with micro needling is a new adjuvant treatment modality of the wound healing cascadebased on the body self-healing mechanisms.
                         OBJECTIVE-:
                          Assesment of safety and efficacy of autologus platelet rich plasma therapy combined with  microneedling on atrophic acne scars.
METHODS: -
46 patients with acne scars of 18-25 years age group underwentthree consecutive sittings of  microneedling combined with PRP procedure, conducted  at an interval of 4 weeks followed by a last assessment done after 3 months of final sitting.
The lesions were classified on Goodman’s qualitative scale and serial photography.
RESULTS:
Two independent dermatologists performed evaluation and follow up at subsequent visits. Majority (34) patients with good response (improvement by Grade 1) constituting to (73.91%) in total. There was an overall improvement in 86.9% of cases without any serious complications.
CONCLUSION: -
Autologus PRP combined with Microneedling is an effective modality in enhancing clinical outcomes and overall cosmetic appearence of acne scars.