European Journal of Molecular & Clinical Medicine

Abstract

Background: Vaginal discharge is one of the commonest problems faced by women. Syndromic management is a benchmark in management of vaginal discharge.
Objectives:
1. To evaluate the efficacy and tolerance of one day combination kit therapy in syndromic management of vaginal discharge in present scenario.
2. To find etiological cause in patients who do not resolve from vaginal discharge after 14 days.
Material and Methods: It was a prospective study done on 100 women in gynaecological opd of a tertiary hospital for a period of 3 months. Patients were evaluated before and after single day AFS kit therapy.
Results: There was excellent response in vaginal discharge(90%). Urinary symptoms and pruritus vulva improved by 80% and 50% respectively. 84% patients had good tolerance and only 2% patients had bad tolerance. 19% patients had Persistent vaginal discharge(PVD) which were due to infectious(42.1%) and non-infectious(57.9%) etiology. Out of these 31.5% had candida albicans, 10.5% had bacterial vaginosis, 15.7% had cervical erosion, 5.2% had cervical polyp and in 37.1% cases no etiology was found.
Conclusion: Combination kits are effective, well tolerable and given in single dose orally in reducing vaginal discharge, pruritus vulva and even urinary symptoms. Persistent vaginal discharge is due to candida and bacterial vaginosis (infectious) and cervical erosion, polyps and unknown cause(non-infectious).