European Journal of Molecular & Clinical Medicine

Abstract

Background: Eosinophilic disorders represent a group of pathologic conditions with highly heterogeneous pathophysiology and clinical presentation and variable prognosis, ranging from asymptomatic or mild, to severe and complex cases, with fatal outcome.
Aims & Objectives: 1. To study the prevalence of Eosniophilia in our part of the country.
2.To study the demographic and clinico-radiological characteristics of cases-presenting with eosinophilia.
Materials and methods: It was a 2 year retrospective observational study conducted at a tertiary care center in Bihar. All patients coming to Hematology department with peripheral blood eosinophilia were studied with a sample size of 200 cases. All cases with normal eosinophil count are excluded from the study. Software used for data analysis was  SPSS version 25 for statistical analysis .
Results: Among 200 patients 57.5% were males and rest 42.5% were females. Maximum number of patients belonged to age group of 11 to 20years (22.5%).52.5 % cases belonged to mild category whereas 39.5% and 8% cases belonged to moderate and severe categories respectively. Fever (46%) was the most common clinical symptom followed by skin rashes (44%) and cough (42.5%). Radiological findings were maximum in patients having severe eosinophilia (71.4%) followed by moderate eosinophilia cases (55.6%). Anemia was most commonly seen in patients with eosinophilia (57.5%) and hemoglobin level was statistically significant with eosinophilia severity with a P value of 0.028.
Conclusion: The study concluded that eosinophilia still is an under-reported public health problem in tropical settings with an estimated prevalence of 0.5-1-case/100,000 population in hospital settings and very few studies have been done so far highlighting the prevalence and etiopathoegensis of eosinophilia in developing countries like ours and many unseen folds still remain to be explored.