European Journal of Molecular & Clinical Medicine

Abstract

BACKGROUND: Cervical ripening is one of the methods employed for induction of labour.
Cervicalripening involves the usage of pharmacological agents or other means to soften, efface or
dilate thecervix to increase the likelihood of a vaginal delivery. Induction of labour (IOL) is the
process
ofinitiatingcontractionsinpregnantpersonswhoarecurrentlynotinlabour,tohelpthemachievevaginaldel
ivery within 24 to 48 hours. OBJECTIVE OF THE STUDY: The objective of the study is
tocompare the efficacy and safety of two different routes of regimen of misoprostol for cervical
ripeningand induction of labour. MATERIALS &METHODS: This prospective comparative
study, wasconducted in the Department of Obstetrics and Gynaecology at Adesh Medical College,
for a periodfrom may January 2021 to June 2021. We enrolled 100 patients in our study. We
divided the
patientsintotwogroupsrandomlyintoGroupAandGroupB.GroupAweadministeredmisoprostolvaginal
lyandGroupBsublingually.Thedoseusedforboththegroupswas25μg.RESULTS&CONCLUSIONS:
In our study, we found that there were no statistically significant differences indemographis,
Bishops Score after induction, number of doses required, complications (foetal distress,meconium
stained liquor and hyper stimulation), maternal side effects and neonatal Apgar
Scoresbetweenthetwogroups.Therewerestatisticallyhighlysignificantdifferencesintheneedforoxytoci
naugmentation between the two groups. Oxytocin augmentation was more in group B in patients
ascomparedto patients in group A.