European Journal of Molecular & Clinical Medicine

Abstract

Aim: To evaluate the role of multidetector computed tomography in acute pancreatitis and
severity of the disease using Modified CT Severity Index.
Material and Methods: This prospective observational study was conducted in the
department of Radio diagnosis, Imaging & Interventional radiology N.S.C.B Subharti
Medical College, CSS Hospital, Meerut among 51 patients in any age group referred to the
radiology department with clinical suspicion of acute pancreatitis for a period from October
2019 to August 2021.Detailed clinical history was taken from the patient relevant clinical
examination done and serum urea and creatinine of the patient was checked.Severity of acute
pancreatitis was analysed using MCTSI.
Results: Most common etiology was found to be gall stones (47.06%) followed by
alcoholism (21.57%). In cases of acute pancreatitis vascular complications such as venous
thrombosis were more commonly associated with acute necrotizing pancreatitis (15.79%)
than acute interstitial pancreatitis (3.13%) and pseudo-aneurysm was seen in association with
acute necrotizing pancreatitis. Majority of the cases were of moderate severity (52.94%). In
subjects categorized as severe according to CT Severity index, recurrence, chronic
pancreatitis and mortality were noted in 3, 5 and 2 subjects respectively. Hence, Modified CT
Severity index was found to have excellent predictability (kappa value=0.85, p<0.01) of
outcome among the subjects with pancreatitis.
Conclusion:MDCT proved to be the imaging modality of choice in patients of AP.MDCT
successfully used to calculate MCTSI which revealed astrong correlation with clinical
outcome and was helpful in assessing disease progression and patient mortality