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  2. Volume 9, Issue 3
  3. Author

Online ISSN: 2515-8260

Volume9, Issue3

Screening of High-Risk Pregnancies by First and Second Trimester Uterine Artery Doppler for Improving Sensitivity in Prediction of Adverse Pregnancy Outcome

    Medabalimi Haritha, Nilofer, Jayasree Gaddipati, Sajana Gogineni, Gayathri K.B.

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 1961-1966

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Abstract

Background: To determine the clinical value of first trimester and second-trimester
uterine artery Doppler indices in the prediction of adverse pregnancy outcome
(preeclampsia, IUGR, unexplained stillbirths).
Materials &Methods:This was a prospective study in which uterine artery Doppler was
performed at 22-24 weeks of gestation 100 high-risk women attending antenatal OPD at
Dr psims & rf in the first trimester between 11 to 13 weeks6days POG for early
pregnancy scan and uterine artery Doppler, followed with second-trimester uterine
artery doppler at the time of anomaly scan 18 to 20weeks from June 2019 to June 2020.
Results: Among the high-risk women in the present study the risk factors are chronic
hypertension (40%), precious pregnancy (10%), overt DM (12%), previous history of
preeclampsia (15%),RPL(10%),SLE (7%), twins (3%), oligohydramnios (3%).
Abnormal uterine artery Doppler indices had the highest sensitivity (100.0%) for
predicting preeclampsia in the mother and the lowest sensitivity (51.4%) for predicting
preterm. For predicting pre-eclampsia, IUGR, neonatal mortality, preterm the
sensitivity of RI was 100%,85.7%,83.3%,51.4% respectively, and the specificity was
92.3%,100%,95.8%,100% respectively. Overall, 35 (35.0%) women had a preterm
delivery, 16 (36%) had a cesarean delivery, and 19 (61%) had a spontaneous vaginal
delivery. Among the preterms, 18(51.4%) died due to prematurity and its associated
complications. The positive predictive value of abnormal uterine artery Doppler was
highest for preeclampsia (36.84%) among all adverse pregnancy outcomes assessed.
Conclusion: Uterine artery Doppler ultrasonography at 22-24 weeks of gestation is a
significant predictor of at least one adverse pregnancy outcome, with the highest
prediction for preeclampsia.
Keywords:
    uterine artery Doppler preeclampsia fetal growth restriction low birth weight adverse obstetric outcome
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(2022). Screening of High-Risk Pregnancies by First and Second Trimester Uterine Artery Doppler for Improving Sensitivity in Prediction of Adverse Pregnancy Outcome. European Journal of Molecular & Clinical Medicine, 9(3), 1961-1966.
Medabalimi Haritha, Nilofer, Jayasree Gaddipati, Sajana Gogineni, Gayathri K.B.. "Screening of High-Risk Pregnancies by First and Second Trimester Uterine Artery Doppler for Improving Sensitivity in Prediction of Adverse Pregnancy Outcome". European Journal of Molecular & Clinical Medicine, 9, 3, 2022, 1961-1966.
(2022). 'Screening of High-Risk Pregnancies by First and Second Trimester Uterine Artery Doppler for Improving Sensitivity in Prediction of Adverse Pregnancy Outcome', European Journal of Molecular & Clinical Medicine, 9(3), pp. 1961-1966.
Screening of High-Risk Pregnancies by First and Second Trimester Uterine Artery Doppler for Improving Sensitivity in Prediction of Adverse Pregnancy Outcome. European Journal of Molecular & Clinical Medicine, 2022; 9(3): 1961-1966.
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