European Journal of Molecular & Clinical Medicine

Abstract

Background: The role of serum uric acid as a risk factor for ischemic stroke in patients with type 2 Diabetes Mellitus is controversial and there is little information about it.
Aim of the study: This study was done to estimate serum uric acid levels in diabetic patients with ischemic stroke and to assess its risk factor potential.
Methods: It is a case control study carried out in the medical ward at Al Hussein Teaching Hospital at Al Nassiriyah city at southern of Iraq from June 2018 till December 2018, carried on 119 patient mean ages is 61.89 years. 56 of them was diabetic patients with ischemic stroke were enrolled as a case group and compared with 63 non diabetic patients presented with ischemic stroke also as a control group, Serum uric acid levels were measured in cases and controls (within 24 hours of stroke). The results were statistically analyzed and studied with other risk factors.
Results: Mean serum uric acid level in cases was 6.02 mg/dl where as it was 5.34mg/dl in controls. Hyperurecemia found in 25% of cases , with significant statistical association with increase in TG Cholesterol level p value is0.028 , and hyperurecemia was significant only in old age diabetic (p value less than 0.05) .
Conclusions: There was no significant statistical association between Serum uric acid level and stroke in type 2 DM, but it found to increase other risk factor for stroke especially in old age group , so it can be considered as a risk factor for ischemic stroke in type 2 DM.